Wearable and At-Home protein monitoring with silicon photonic chips

SiPhox, a Khosla Ventures, Intel Capital, and Y Combinator-backed startup, is commercializing next-generation diagnostics and label-free proteomics using Silicon Photonics, a platform technology for optics miniaturization that has revolutionized the data center industry over the last two decades. SiPhox's technology provides the power of large laboratory instruments in a handheld device that accepts disposable silicon photonic chip sensors.

Role Overview:

This is an opportunity to join a high-growth startup at its first major inflection point: We have a validated functional first-generation platform that is ready for commercialization and scale-up, as well as next-generation development.

SiPhox is embarking on an ambitious effort to develop and commercialize a large menu of immunoassay targets on its multiplexed clinical-grade, validated, at-home diagnostics platform. We are looking for a scientist who will collaborate with our engineers, process development and product development teams to build this expanded menu on our platform and help bring it through validation.

Responsibilities

Help with execution of immunoassays, recording of procedures, analysis and interpretation of results under supervision of senior scientists Maintain reagent stocks, solutions and records of these stocks and solutions Characterize antibodies and antigens using spectrophotometry, SDS-PAGE and label-free interaction analysis Collaborate with the process and chemistry team to ensure the development of robust and scalable processes for assay manufacturing and quality control. Qualifications

BS in biochemistry, biophysics, analytical chemistry, bioengineering or a related discipline Acquaintance and practical ability with basic laboratory procedures, established techniques, instruments and equipment is required Attention to detail and good record keeping skills are essential Familiarity with statistical principles applicable to assessment of assay performance Experience in computational analysis of data sets using general-purpose programming language (such as Python, R, or Matlab) is a plus Experience with POC/At-home devices is a plus Personal characteristics:

Sets and achieves tough stretch goals; delivers outstanding, measurable results Absolute personal integrity and credibility; acts small and delivers outsized results Passion for excellence Creative, thinks out of the box COMPENSATION & OPPORTUNITY:

Compensation is competitive including comprehensive benefits, Lifetime Gym Membership (luxury gym 1 block from the office), and significant stock options

We are developing a new paradigm for consumer health tech wearables by replacing a 100lb optical instrument with an area of silicon smaller than a postage stamp.