Gene regulators are responsible for interpreting the human genome by switching genes on and off at the correct time in the correct cells, and their malfunction is common across many diseases. While our tools to measure and manipulate DNA itself have matured (DNAseq, CRISPR), we lack effective tools for studying gene regulators.
As a result, gene regulators are often passed over in favor of protein families with established experimental approaches, leading to few drug candidates for this target class. There are over 2,200 proteins in this family, yet less than 2% of them are targeted with FDA-approved drugs. Many of these approved drugs were discovered by serendipity, so we instead are pursuing a systematic approach for the discovery and development of gene regulator drugs.
Our platform measures a drug’s ability to disrupt a gene regulator within its natural, non-engineered cellular environment. Furthermore, a single experiment using the platform measures activity for hundreds of gene regulators simultaneously, providing information on in-cell drug activity and specificity in a single experiment. To accomplish this, we combine innovative cell processing with high-sensitivity quantitative proteomics and advanced downstream analytics.
Talus Bioscience is a venture-backed early-stage biotechnology startup working to develop new therapies for incurable cancers. At Talus, we believe nothing is undruggable. We build the technology to bring drug development back to where it matters, inside the live human cell.
Exciting things are happening at Talus…come join us!
Talus is looking for a Director/Sr. Director of Business Development to join our team, reporting to the CEO. This role will ideally be on-site in Seattle, but remote work will be considered for the right candidate. The goal of this role is to own the business development strategy for the entire organization, identifying opportunities for partnership to fully realize the value of Talus’ technology platform. They will work directly within Talus Bio’s leadership team and across the entire organization.
Essential Job Responsibilities
Talus believes that our staff should reflect the diversity of our community. We are committed to hiring and advancing staff that represent voices from traditionally underrepresented populations. We are committed as an organization to foster better cultural competency, equity, and diversity. We're open to a variety of backgrounds and experiences, and all talent is welcome and encouraged to apply, even if not all of the required qualifications are met.
Required Skills and Experience
Preferred Skills and Experience
Benefits At Talus, we’re proud to offer a comprehensive benefits package that is top of class for a small startup:
COVID Precautions We value the safety of our employees and have put in measures to reduce the risk of COVID that include: Optional remote interview process Personal protective equipment provided and required Weekly COVID testing and reporting protocols
Talus Bioscience provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.
We're looking for people looking to join an interdisciplinary team focused on bringing drug discovery out of the test tube and into the cell. In particular, experts in: